Application

Research CategoryNeuroscience

Anti-Striatin Antibody detects level of Striatin & has been published & validated for use in IP, WB & IC.

Western blot: 1:500-1:1,000. The antibody reacts with the ~110 kDa striatin protein in 293 cell lysate.

Immunocytochemistry: 1:500

Immunoprecitation: 3 µL recommended as starting point.

Optimal working dilutions must be determined by the end user.

Research Sub CategorySynapse & Synaptic Biology

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Striatin is found in all mammalian cells and may be involved in vesicular transport, dendrite growth and cellular signalling. It binds Protein phosphatase 2A (PP2A) A and C subunits and calmodulin and appears to modulate PP2A activity. It also binds the human homolog of the yeast protein, Mob1, which has been implicated in mitotic progression in yeast. It is a member of a family of proteins that also include SG2NA (striatin 3) and Zinedin (striatin 4).

Immunogen

Synthetic Striatin peptide.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

Rabbit serum. Liquid containing 40% glycerol and 0.02% sodium azide.

Specificity

Reacts with Striatin. No cross reactivity with SG2NA.

Storage and Stability

Maintain at -20°C in undiluted for up to 12 months after date of receipt. For long-term storage, may be stored at -80°C. Avoid repeated freeze/thaw cycles at temperatures below -20°C.